Effects of L-tyrosine on brain monoamines in rats given intravenous amphetamine.


A computer-controlled device was used to deliver intravenous injections of saline or d-amphetamine, in patterns resembling those of animals trained to self-administer the drug via lever pressing. Amphetamine, administered in this manner (over the course of an 8 hr test session), induced a 27% decrease in brain norepinephrine. The injection of the amino acid… (More)


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