Effects of Isoteoline in Experimental Tests for Memory and Sedation in Mice

  title={Effects of Isoteoline in Experimental Tests for Memory and Sedation in Mice},
  author={Maria D Zhelyazkova-Savova},
Isoteoline (IST) has been previously shown to possess anxiolytic activity in models of mice and rats. The aim of the present study was to examine this compound for potential memory-impairing and sedative effects. IST was compared with scopolamine and diazepam known for their anterograde amnesia, in respect to information acquisition. Diazepam served also as a sedative standard. Passive avoidance test was used to explore the effect of the drugs on the cognitive processes. Memory components such… 

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