Effects of Interferon-γ on Neuronal Infections

  title={Effects of Interferon-γ on Neuronal Infections},
  author={Martin E Rottenberg and Krister Kristensson},
IFN-γ is released in the brain, not only during acute infectious diseases or immunological reactions, but also for extended periods of time after clearance of infectious virus and during viral latency. In this review, we focus on the role of IFN-γ in the interaction between a neuron and a pathogen, that is, the role in implementation of microbial destruction, stasis or persistence, its potential neuroprotective or toxic effects, and how this cytokine may affect neuronal function and the… CONTINUE READING

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