Effects of Imidazoline Drugs on Tyrosine and Tryptophan Hydroxylase Activity in Rat Brain in Vivo

@article{Esteban1999EffectsOI,
  title={Effects of Imidazoline Drugs on Tyrosine and Tryptophan Hydroxylase Activity in Rat Brain in Vivo},
  author={S. Esteban and A. Sastre-Coll and J. Garc{\'i}a-Sevilla},
  journal={Annals of the New York Academy of Sciences},
  year={1999},
  volume={881}
}
Dexmedetomidine Reduces Long-term Potentiation in Mouse Hippocampus
TLDR
Investigation of the effects of dexmedetomidine on two forms of synaptic plasticity—long-term potentiation (LTP) and paired-pulse facilitation—in the CA1 region of mouse hippocampal slices found it impairs LTP in area CA1 of the mouse hippocampus via imidazoline type 2 receptors and &agr;2-adrenoceptors. Expand

References

Immunocytochemical localization of an imidazoline receptor protein in the central nervous system
TLDR
I-receptor(s) localize to a highly restricted network of neurons in the CNS and circumventricular regions lying outside of the blood-brain barrier and are heavily represented in sensory processing centers and the visceral nervous system. Expand