Effects of Hydrogenized Water on Intracellular Biomarkers for Antioxidants, Glucose Uptake, Insulin Signaling and SIRT 1 and Telomerase Activity

@article{Settineri2019EffectsOH,
  title={Effects of Hydrogenized Water on Intracellular Biomarkers for Antioxidants, Glucose Uptake, Insulin Signaling and SIRT 1 and Telomerase Activity},
  author={R. Settineri and Jin Ji and C-H Luo and R. Ellithorpe and G. F. D. Mattos and Steven Rosenblatt and J. Lavalle and Antonio Jinenez and S. Ohta and G. Nicolson},
  journal={American Journal of Food and Nutrition},
  year={2019},
  volume={4},
  pages={161-168}
}
Hydrogen has been shown in several clinical trials to be completely safe without adverse events and there are no warnings in the literature of its toxicity or adverse effects during long-term exposure. Molecular hydrogen has proven useful and convenient as a novel antioxidant and modifier of gene expression in many conditions where oxidative stress and changes in gene expression result in cellular damage. Our intracellular biomarker studies have shown that a hydrogenized water drink formula… Expand

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References

SHOWING 1-10 OF 27 REFERENCES
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals
Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine.
  • S. Ohta
  • Chemistry, Medicine
  • Pharmacology & therapeutics
  • 2014
Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation.
Cellular antioxidant activity (CAA) assay for assessing antioxidants, foods, and dietary supplements.
Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism
Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome
Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells
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3
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