Effects of Hoe 140 on systemic depressor responses to bradykinin and mesenteric vascular reactivity in vivo in pregnant Wistar-Kyoto rats.

@article{Chu1994EffectsOH,
  title={Effects of Hoe 140 on systemic depressor responses to bradykinin and mesenteric vascular reactivity in vivo in pregnant Wistar-Kyoto rats.},
  author={Zhi-yong Chu and Lawrence J Beilin},
  journal={Clinical and experimental pharmacology & physiology},
  year={1994},
  volume={21 2},
  pages={137-40}
}
1. To examine possible changes in vascular reactivity to exogenous bradykinin (BK) and the possible role of endogenous BK in reduced mesenteric vascular reactivity in pregnant rats. The authors studied the effects of Hoe 140 on systemic depressor responses to BK and on mesenteric vascular reactivity in in situ blood-perfused mesenteric resistance vessels of 18-20 day pregnant and age-matched non-pregnant Wistar-Kyoto rats (WKY). 2. Mean intra-arterial blood pressure (MBP) of pregnant rats was… CONTINUE READING

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