Effects of Helicobacter pylori infection on gastric parietal cells and E-cadherin in Mongolian gerbils.

@article{Murakami2013EffectsOH,
  title={Effects of Helicobacter pylori infection on gastric parietal cells and E-cadherin in Mongolian gerbils.},
  author={Motonobu Murakami and Mayu Fukuzawa and Mika Yamamoto and Kanako Hamaya and Yuumi Tamura and Akiko Sugiyama and Rei Takahashi and Toshiko Murakami and Kikuko Amagase and Koji Takeuchi},
  journal={Journal of pharmacological sciences},
  year={2013},
  volume={121 4},
  pages={305-11}
}
Atrophic gastritis caused by infection with Helicobacter pylori is characterized by parietal cell loss, which is a main risk factor for gastric cancer. Parietal cells play a crucial role in the regulation of cell lineage maturation and proliferation in the gastric units. Among the classical cadherins, E-cadherin plays an important role not only in epithelial cell-cell connections, but also in the maintenance of epithelial polarity and gastric glandular architecture and regulation of cell… CONTINUE READING

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