Effects of Halothane and Chloroform on the Liver in Protein-deficient Mice.

@article{Wingard1965EffectsOH,
  title={Effects of Halothane and Chloroform on the Liver in Protein-deficient Mice.},
  author={D W Wingard and Heather S Davis and Dan Leonard},
  journal={British journal of anaesthesia},
  year={1965},
  volume={37},
  pages={
          103-10
        }
}
A single 45-minute exposure to halothane did not cause demonstrable pathological liver changes when administered to mice in an atmosphere of air or oxygen regardless of whether the diet was normal or low in protein. Similarly, increased inhaled oxygen tensions per se had no influence on liver changes. The well-known hepatotoxicity of chloroform was… CONTINUE READING