Effects of Granulocyte-Colony Stimulating Factor on the Polymorphonuclear Leukocyte Activity and the Course of Sepsis in Rats with Experimental Peritonitis

@article{Gurleyik2005EffectsOG,
  title={Effects of Granulocyte-Colony Stimulating Factor on the Polymorphonuclear Leukocyte Activity and the Course of Sepsis in Rats with Experimental Peritonitis},
  author={Gunay Gurleyik and Gulderen Yanikkaya and Emin Gurleyik and Erol Ozturk and Ender Dulundu and Abdullah Sağlam},
  journal={Surgery Today},
  year={2005},
  volume={37},
  pages={401-405}
}
Polymorphonuclear leucocytes (PML) play an essential role in the host immune response to severe infections. The effects of granulocyte-colony stimulating factor (G-CSF) on the PML immune functions during serious abdominal infection and course of sepsis, and on the survival in rats with peritonitis are the main subjects of this study. The first phase of the study was carried out on 30 Wistar-albino rats equally divided into three groups; Group 1 (control) sham laparotomy; Group 2 (peritonitis… CONTINUE READING

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