Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices

@article{Guo2012EffectsOG,
  title={Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices},
  author={Chengxian Guo and Q. Pei and Ji-Ye Yin and Xiang-dong Peng and B. Zhou and Ying-chun Zhao and Lan-xiang Wu and Xiang-guang Meng and Guo Wang and Q. Li and D. Ouyang and Z. Liu and W. Zhang and H. Zhou},
  journal={Xenobiotica},
  year={2012},
  volume={42},
  pages={784 - 790}
}
Ginkgo biloba extract (GBE) is one of the most widely used herbal medicines in the world. It is often administered in combination with statins to treat diseases, especially some nervous system disorders. We aimed to investigate the influences of GBE on pharmacokinetics and efficacy of atorvastatin, which are currently unclear. Sixteen volunteers received a single oral dose of 40 mg atorvastatin, followed by a wash-out period of at least 5 days. Then the volunteers took 360 mg GBE daily for 14… Expand
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