Effects of Gingko biloba extract on tissue distribution of fluoxetine and venlafaxine in rats

  title={Effects of Gingko biloba extract on tissue distribution of fluoxetine and venlafaxine in rats},
  author={Saad Abdulrahman Hussain and Fatima Adnan Alzubaidi and Hayder Obayes Hashem},
  journal={Journal of Intercultural Ethnopharmacology},
  pages={234 - 238}
Objective: There are many concerns about the interactions of herbal products with conventional drugs, which are mostly used as multiple drug treatment approach. The present study was designed to evaluate the effect of long-term use of Ginkgo biloba extract (GK) on the absorption and tissue distribution of fluoxetine and venlafaxine. Materials and Methods: 46 Wistar rats are utilized and allocated into 8 groups; 2 groups administered the vehicle and saved as control; 4 groups are treated with… Expand
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Effects of Ginkgo biloba Extract on the Oral Bioavailability of Fluoxetine and Venlafaxine in Rats
GK extract shows no physicochemical interactions with fluoxetine or venlafaxine, and the results showed that GK extract has no significant effects on the bioavailability of fluoxettine and venl Lafaxine. Expand
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