Effects of GPi stimulation on human thalamic neuronal activity.

  title={Effects of GPi stimulation on human thalamic neuronal activity.},
  author={Erwin B. Montgomery},
  journal={Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology},
  volume={117 12},
OBJECTIVE Determine the effects of globus pallidus interna (GPi) deep brain stimulation (DBS) on ventral oralis posterior nucleus of the thalamic (Vop) neuronal activity. METHODS Microelectrode recordings in Vop during high frequency DBS GPi in a patient with dystonia. RESULTS Twelve (48%) of 25 neurons in five locations neurons decreased their average discharge frequency, 2 (8%) increased and 11(44%) demonstrated no overall change. The patterns of responses were complex with periods of… CONTINUE READING