Effects of GABA agonists on Herxheimer microshock in guinea pigs

Abstract

In this paper we describe the first observation of GABA inhibition in an experimental model of asthmain vivo. Guinea-pigs were actively sensitized with ovalbumin i.p. and 20 days later the Herxheimer microshock was performed. GABA and (−)-baclofen injected 20 min previously significantly prevented the development of microshock. Therefore GABAergic drugs… (More)
DOI: 10.1007/BF01988032

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@article{Luzzi1986EffectsOG, title={Effects of GABA agonists on Herxheimer microshock in guinea pigs}, author={Stephen Luzzi and Sergio Franchi-Micheli and Mario Ciuffi and Lucilla Zilletti}, journal={Agents and Actions}, year={1986}, volume={18}, pages={245-247} }