Effects of Food Intake on the Relative Bioavailability of Amifampridine Phosphate Salt in Healthy Adults.


PURPOSE Amifampridine (3,4-diaminopyridine) has been approved in the European Union for the treatment of Lambert-Eaton myasthenic syndrome. Amifampridine has a narrow therapeutic index, and supratherapeutic exposure has been associated with dose-dependent adverse events, including an increased risk for seizure. This study assessed the effect of food on the… (More)
DOI: 10.1016/j.clinthera.2015.05.498


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics