Effects of Flaxseed Oil on Lead Acetate-Induced Neurotoxicity in Rats

@article{Moneim2011EffectsOF,
  title={Effects of Flaxseed Oil on Lead Acetate-Induced Neurotoxicity in Rats},
  author={Ahmed E Abdel Moneim and Mohamed A Dkhil and saleh al-Quraishy},
  journal={Biological Trace Element Research},
  year={2011},
  volume={144},
  pages={904-913}
}
It is well known that chronic exposure to lead (Pb+2) alters a variety of behavioral tasks in rats and mice. Here, we investigated the effect of flaxseed oil (1,000 mg/kg) on lead acetate (20 mg/kg)-induced brain oxidative stress and neurotoxicity in rats. The levels of Pb+2, lipid peroxidation, nitric oxide (NO), and reduced glutathione (GSH) and the activity of catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR), glutathione-S-transferase (GST), and glutathione peroxidase… CONTINUE READING
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