Effects of Fish Oil and Grape Seed Extract Combination on Hepatic Endogenous Antioxidants and Bioactive Lipids in Diet-Induced Early Stages of Insulin Resistance in Rats

@article{Taltavull2020EffectsOF,
  title={Effects of Fish Oil and Grape Seed Extract Combination on Hepatic Endogenous Antioxidants and Bioactive Lipids in Diet-Induced Early Stages of Insulin Resistance in Rats},
  author={N{\'u}ria Taltavull and Bernat Miralles-P{\'e}rez and M. R. Nogu{\'e}s and S. Ramos-Romero and L. M{\'e}ndez and I. Medina and J. L. Torres and M. Romeu},
  journal={Marine Drugs},
  year={2020},
  volume={18}
}
  • Núria Taltavull, Bernat Miralles-Pérez, +5 authors M. Romeu
  • Published 2020
  • Chemistry, Medicine
  • Marine Drugs
  • Diacylglycerols (DAG) and ceramides have been suggested as early predictors of insulin resistance. This study was aimed to examine the combined effects of fish oil (FO) and grape seed extract (GSE) on hepatic endogenous antioxidants, DAG and ceramides in diet-induced early stages of insulin resistance. Thirty-five rats were fed one of the following diets: (1) a standard diet (STD group), (2) a high-fat high-sucrose diet (HFHS group), (3) an HFHS diet enriched with FO (FO group), (4) an HFHS… CONTINUE READING
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