Effects of Ficus umbellata (Moraceae) Aqueous Extract and 7-Methoxycoumarin on Scopolamine-Induced Spatial Memory Impairment in Ovariectomized Wistar Rats

@article{Zingu2018EffectsOF,
  title={Effects of Ficus umbellata (Moraceae) Aqueous Extract and 7-Methoxycoumarin on Scopolamine-Induced Spatial Memory Impairment in Ovariectomized Wistar Rats},
  author={St{\'e}phane Zingu{\'e} and Harquin Simplice Foyet and Sefirin Djiogue and Yannick Ezo'o Ezo'o and Herv{\'e} Herv{\'e} Ngatanko Aba{\"i}ssou and Pafroumi Fachagbo and Dieudonn{\'e} Njamen},
  journal={Behavioural Neurology},
  year={2018},
  volume={2018}
}
The present work was undertaken to evaluate the ability of F. umbellata aqueous extract and its major component 7-methoxycoumarin (MC) to improve scopolamine-induced spatial memory impairment in ovariectomized Wistar rats. For this to be done, 10 sham-operated and 30 postmenopausal-like rats were randomly distributed in eight groups (n = 5) and treated with distilled water (2 mL/250 g), estradiol valerate (1 mg/kg BW), piracetam (1.5 mg/kg BW), F. umbellata aqueous extract (50 and 200 mg/kg BW… 
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