Effects of FGF-2 on metaphyseal fracture repair in rabbit tibiae

@article{Chen2003EffectsOF,
  title={Effects of FGF-2 on metaphyseal fracture repair in rabbit tibiae},
  author={Wei-Jia Chen and Seiya Jingushi and Ikuo Aoyama and Jun Anzai and Goh Hirata and Makoto Tamura and Yukihide Iwamoto},
  journal={Journal of Bone and Mineral Metabolism},
  year={2003},
  volume={22},
  pages={303-309}
}
Fibroblast growth factor-2 (FGF-2) has been found to have stimulatory effects on fracture repair at diaphysis, while its effect on metaphyseal fracture repair, where spongiosal bone is dominant, has not been studied. This study was conducted to investigate the effect of FGF-2 on metaphyseal fracture healing in a rabbit proximal tibial metaphyseal model. The proximal tibial metaphysis of 6-month-old Japanese white rabbits was osteotomized bilaterally. Then 400 µg of FGF-2, mixed with gelatin… CONTINUE READING