Effects of FG7142 and immobilization stress on the gene expression in the neocortex of mice

@article{Kurumaji2008EffectsOF,
  title={Effects of FG7142 and immobilization stress on the gene expression in the neocortex of mice},
  author={Akeo Kurumaji and Takashi Ito and Shin-ichi Ishii and Toru Nishikawa},
  journal={Neuroscience Research},
  year={2008},
  volume={62},
  pages={155-159}
}
Several psychiatric disorders are often precipitated or exacerbated by exposure to stressors. FG7142 (N-methyl-beta-carboline-3-carboxamide), a partial inverse agonist of benzodiazepine receptors, mimics the physiological (an increased release in the adrenal steroid hormone) and neurochemical (an enhanced neurotransmission of monoamines) changes induced by stressful stimuli. We examined the effects of FG7142 and immobilization stress on the gene expression of the mouse neocortex in order to… CONTINUE READING
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