Effects of Ethanol, Temperature, and Endogenous Regulatory Factors on the Characteristics of Striatal Opiate Receptors

@article{Hoffman1984EffectsOE,
  title={Effects of Ethanol, Temperature, and Endogenous Regulatory Factors on the Characteristics of Striatal Opiate Receptors},
  author={Paula L. Hoffman and Cathie T. Chung and Boris Tabakoff},
  journal={Journal of Neurochemistry},
  year={1984},
  volume={43}
}
Abstract: Ethanol can alter the affinity of mouse striatal opiate receptors for their ligands, and the present studies were aimed at determining the importance of the receptor microenvironment for this effect of ethanol. Changing the temperature of the binding assay, and thus altering the properties of neuronal membrane lipids, resulted in changes in the observed affinity of striatal binding sites for dihydromorphine (DHM), but not for d‐Ala2, d‐Leu5‐enkephalin (ENK). The changes in temperature… 
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