Effects of Early and Recent Adverse Experiences on Adrenal Response to Psychosocial Stress in Depressed Adolescents

@article{Rao2008EffectsOE,
  title={Effects of Early and Recent Adverse Experiences on Adrenal Response to Psychosocial Stress in Depressed Adolescents},
  author={Uma Rao and Constance L. Hammen and Luis R. Ortiz and Li-Ann Chen and Russell E. Poland},
  journal={Biological Psychiatry},
  year={2008},
  volume={64},
  pages={521-526}
}
BACKGROUND As observed in depressed adults, there is considerable variability in the degree and direction of hypothalamic-pituitary-adrenal (HPA) dysfunction in depressed adolescents. The variability in HPA findings may be attributed to experiential factors. METHODS A modified version of a standard psychosocial stressor used in adults, the Trier Social Stress Test (TSST), was administered to 30 adolescents with major depressive disorder and 25 healthy adolescent volunteers. Cortisol… CONTINUE READING