Effects of ER stress on unfolded protein responses, cell survival, and viral replication in primary effusion lymphoma.

@article{Shigemi2016EffectsOE,
  title={Effects of ER stress on unfolded protein responses, cell survival, and viral replication in primary effusion lymphoma.},
  author={Zenpei Shigemi and Yusuke Baba and Naoko Hara and Jumpei Matsuhiro and Hiroki Kagawa and Tadashi Watanabe and Masahiro Fujimuro},
  journal={Biochemical and biophysical research communications},
  year={2016},
  volume={469 3},
  pages={565-72}
}
Primary effusion lymphoma (PEL), a subtype of non-Hodgkin's B-lymphoma, is an aggressive neoplasm caused by Kaposi's sarcoma-associated herpesvirus (KSHV) in immunosuppressed patients. Endoplasmic reticulum (ER) stress induces activation of the unfolded protein response (UPR), which induces expression of ER chaperones, which in turn decrease ER stress… CONTINUE READING