Effects of Dopamine Receptor Blockade on Cerebral Blood Flow Response to Somatosensory Stimulation in the Unanesthetized Rat

@article{Esaki2002EffectsOD,
  title={Effects of Dopamine Receptor Blockade on Cerebral Blood Flow Response to Somatosensory Stimulation in the Unanesthetized Rat},
  author={Takanori Esaki and Yoshiaki Itoh and Kazuaki Shimoji and Michelle P Cook and Jane Jehle and Louis Sokoloff},
  journal={Journal of Pharmacology and Experimental Therapeutics},
  year={2002},
  volume={303},
  pages={497 - 502}
}
  • T. Esaki, Y. Itoh, +3 authors L. Sokoloff
  • Published 1 November 2002
  • Biology, Medicine
  • Journal of Pharmacology and Experimental Therapeutics
Local cerebral blood flow (CBF) was determined in 30 cerebral structures, including four structures of the whisker-to-barrel cortex sensory pathway, by the quantitative autoradiographic [14C]iodoantipyrine method during unilateral vibrissal stimulation in rats administered 0.1 or 1.0 mg/kg haloperidol or its control vehicle intravenously. The low dose of haloperidol had no significant effects on resting CBF or its enhancement by vibrissal stimulation. By standard t tests, the high dose… 
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