Effects of Different Triglyceride Saturated Fatty Acids on Tissue Lipid Level, Fatty Acid Composition, Fecal Steroid Excretion, Prostacyclin Production, and Platelet Aggregation in Rats.

@article{Abe1993EffectsOD,
  title={Effects of Different Triglyceride Saturated Fatty Acids on Tissue Lipid Level, Fatty Acid Composition, Fecal Steroid Excretion, Prostacyclin Production, and Platelet Aggregation in Rats.},
  author={K Abe and Katsumi Imaizumi and Michihiro Sugano},
  journal={Bioscience, biotechnology, and biochemistry},
  year={1993},
  volume={57 2},
  pages={
          247-52
        }
}
Male Sprague-Dawley rats were fed for 3 weeks cholesterol-enriched diets containing 7% interesterified fats in which saturated fatty acids, lauric, myristic, palmitic, and stearic acids, were the sole variable. The dietary fat was composed of 50% saturated fatty acid, 30% oleic acid, 14% linoleic acid, and 6% α-Iinolenic acid (P/S =0.4, n-6/n-3 =2.3). There was no difference in food intake, body weight gain, or liver and epididymal adipose tissue weight among the groups, although the apparent… 
Effects of highly hydrogenated soybean oil and cholesterol on plasma, liver cholesterol, and fecal steroids in rats
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It is suggested that not only the high concentration of stearic acid but also its uneven distribution in HSO-triacylglycerol contributed to the reduction in intestinal cholesterol absorption in rats.
Metabolism of dietary stearic acid relative to other fatty acids in human subjects.
  • E. Emken
  • Chemistry, Medicine
    The American journal of clinical nutrition
  • 1994
TLDR
The results indicate that metabolic differences between 18:0 and 16:0 only partially explain the difference in the cholesterolemic effect reported for these saturated fatty acids.
Effect of feeding thoroughbred horses a high unsaturated or saturated vegetable oil supplemented diet for 6 months following a 10 month fat acclimation.
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No apparent adverse effects of feeding a diet supplemented with either an unsaturated or saturated vegetable oil for 6 months at Approximately 20% DE after 10 months at approximately 12% DE were identified and there were no apparent disadvantages of feeding either a saturated or unsaturated vegetable oil supplemented diet compared with an uns saturated one.

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