Effects of Dietary Different Doses of Copper and High Fructose Feeding on Rat Fecal Metabolome.

@article{Wei2015EffectsOD,
  title={Effects of Dietary Different Doses of Copper and High Fructose Feeding on Rat Fecal Metabolome.},
  author={Xiaoli Wei and Ming Song and Xinmin Yin and Dale A. Schuschke and Imhoi Koo and Craig J. McClain and Xiang Zhang},
  journal={Journal of proteome research},
  year={2015},
  volume={14 9},
  pages={
          4050-8
        }
}
The gut microbiota plays a critical role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Increased fructose consumption and inadequate copper intake are two critical risk factors in the development of NAFLD. To gain insight into the role of gut microbiota, fecal metabolites, obtained from rats exposed to different dietary levels of copper with and without high fructose intake for 4 weeks, were analyzed by comprehensive two-dimensional gas chromatography time-of-flight mass… 

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