Effects of Depression and Serotonergic Antidepressants on Bone: Mechanisms and Implications for the Treatment of Depression

@article{Fernandes2015EffectsOD,
  title={Effects of Depression and Serotonergic Antidepressants on Bone: Mechanisms and Implications for the Treatment of Depression},
  author={Brisa Fernandes and Jason M. Hodge and Julie A. Pasco and Michael Berk and Lana J. Williams},
  journal={Drugs \& Aging},
  year={2015},
  volume={33},
  pages={21-25}
}
Osteoporosis is a chronic skeletal disease marked by microarchitectural deterioration of the bone matrix and depletion of bone mineral density (BMD), with a consequent increased risk for fragility fractures. It has been frequently associated with depression, which is also a chronic and debilitating disorder with high prevalence. Selective serotonin reuptake inhibitors (SSRIs), first-line agents in the pharmacological treatment of mood and anxiety disorders, have also been shown to negatively… Expand
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