Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy.

@article{Stevens2000EffectsOD,
  title={Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy.},
  author={Martin J. Stevens and Irina G. Obrosova and Xuesong Cao and Carol Van Huysen and Douglas A. Greene},
  journal={Diabetes},
  year={2000},
  volume={49 6},
  pages={1006-15}
}
Experimental diabetic peripheral neuropathy (DPN) is marked by impaired nerve conduction velocity (NCV), reduced nerve blood flow (NBF), and a variety of metabolic abnormalities in peripheral nerve that have been variously ascribed to hyperglycemia, abnormal fatty acid metabolism, ischemic hypoxia, and/or oxidative stress. Some investigators propose that… CONTINUE READING