Effects of Coriolus versicolor polysaccharides peptides on electric activity of mediobasal hypothalamus and on immune function in rats.

@article{Yu1996EffectsOC,
  title={Effects of Coriolus versicolor polysaccharides peptides on electric activity of mediobasal hypothalamus and on immune function in rats.},
  author={G-P. Yu and Qiuzhen Yin and Ya-e Hu and Z. W. Yin and Zhengmeng Gu and Z. N. Qian and Zhong-Ming Qian},
  journal={Zhongguo yao li xue bao = Acta pharmacologica Sinica},
  year={1996},
  volume={17 3},
  pages={
          271-4
        }
}
AIM The nervous mechanism of the immune potentiating effect of Coriolus versicolor polysaccharides peptides (PSP) was studied in Wistar rats. METHODS The unit discharge of the mediobasal hypothalamus (MBH) neurons was recorded extracellularly and the lymphocyte proliferation was measured. RESULTS PSP 1 g.kg-1 ig for 5 d increased the T-lymphocytes and promoted T-lymphocyte proliferation in spleen and peripheral blood. This promoting effect of PSP was blocked by MBH lesion. PSP increased the… CONTINUE READING