Effects of Clobazam and Its Active Metabolite on GABA‐Activated Currents in Rat Cerebral Neurons in Culture

@article{Nakamura1996EffectsOC,
  title={Effects of Clobazam and Its Active Metabolite on GABA‐Activated Currents in Rat Cerebral Neurons in Culture},
  author={Fumihiro Nakamura and S. Suzuki and Shigeko Nishimura and Kazuichi Yagi and M Seino},
  journal={Epilepsia},
  year={1996},
  volume={37}
}
Summary: Purpose: The antiepileptic effects of clobazam, a 1,5‐benzodiazepine, have been well documented in animal experiments and clinical trials. However, the drug's mechanisms of antiepileptic actions are still undetermined. The purpose of this study was to learn how clobazam and its active metabolite modulate γ‐aminobutyric acid (GABA)‐activated currents in rat cerebral neurons in culture. 

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