Effects of Cell Population Heterogeneity on the Dynamics of Cell Populations

@inproceedings{Mantzaris2003EffectsOC,
  title={Effects of Cell Population Heterogeneity on the Dynamics of Cell Populations},
  author={Nikos V. Mantzaris},
  year={2003}
}
A novel methodological and computational framework for the quantitative assessment of the effects of cell popu lation heterogeneity on the dynamics of cell populations is presented. We focus on populations of cells carrying an artificial genetic network, consisting of a system of two promoterrepressor pairs. Detailed numerical simulations ind icate that taking into account cell population heterogeneity leads to agreement wi th experimental data, while neglecting it results in significant… CONTINUE READING