Effects of Celebrex and Zyflo on BOP-Induced Pancreatic Cancer in Syrian Hamsters

@article{Wenger2002EffectsOC,
  title={Effects of Celebrex and Zyflo on BOP-Induced Pancreatic Cancer in Syrian Hamsters},
  author={F. Wenger and M. Kilian and P. Achucarro and D. Heinicken and I. Schimke and H. Guski and C. Jacobi and J. M. M{\"u}ller},
  journal={Pancreatology},
  year={2002},
  volume={2},
  pages={54 - 60}
}
Background/Aims: Selective inhibition of eicosanoid synthesis decreases inflammation, however, it is still unknown whether oxidative stress and carcinogenesis might be influenced in ductal pancreatic ductal cancer as well. Methods: 120 male hamsters were randomized into 8 groups (n = 15). While control group 1–4 received 0.5 ml normal saline s.c. weekly for 16 weeks, groups 5–8 were injected 10 mg BOP/kg body weight to induce pancreatic cancer. After establishment of pancreatic cancer, groups 1… Expand
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  • M. Edelman, D. Watson, +10 authors Mark Green
  • Medicine
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2008
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