Effects of Cav3.2 channel mutations linked to idiopathic generalized epilepsy.

@article{Khosravani2005EffectsOC,
  title={Effects of Cav3.2 channel mutations linked to idiopathic generalized epilepsy.},
  author={Houman Khosravani and Christopher Bladen and David B. Parker and Terrance P. Snutch and John E. McRory and Gerald W Zamponi},
  journal={Annals of neurology},
  year={2005},
  volume={57 5},
  pages={745-9}
}
Heron and colleagues (Ann Neurol 2004;55:595-596) identified three missense mutations in the Cav3.2 T-type calcium channel gene (CACNA1H) in patients with idiopathic generalized epilepsy. None of the variants were associated with a specific epilepsy phenotype and were not found in patients with juvenile absence epilepsy or childhood absence epilepsy. Here… CONTINUE READING