Effects of Carmustine and Lomustine on Arylamine N-Acetyltransferase Activity and 2-Aminofluorene-DNA Adducts in Rat Glial Tumor Cells


Carmustine and lomustine are nitrosourea antitumor chemotherapeutic agents which were used to determine whether or not they could affect arylamine N-acetyltransferase (NAT) activity and DNA-2-aminofluorene adducts in rat glial tumor cell line (C6 glioma). The NAT activity was measured by high preformance liquid chromatography (HPLC) assaying for the amounts… (More)
DOI: 10.1023/A:1007573609158


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