Effects of Carbonic Anhydrase Inhibition on the Responsiveness of Laryngeal Receptors in Cats to CO2

  title={Effects of Carbonic Anhydrase Inhibition on the Responsiveness of Laryngeal Receptors in Cats to CO2},
  author={Z. Wang and A. Bradford and R. O’Regan},
  journal={Experimental Physiology},
  • Z. Wang, A. Bradford, R. O’Regan
  • Published 2001
  • Chemistry, Medicine
  • Experimental Physiology
  • The effects of carbonic anhydrase inhibition on the responsiveness to CO2 of pressure‐sensitive laryngeal receptors were examined in anaesthetised, paralysed cats. Laryngeal CO2‐sensitive receptors from the superior laryngeal nerve were selected by their responsiveness to intralaryngeal pressure and to perfusion of solution equilibrated with 9% CO2. The carbonic anhydrase inhibitor, methazolamide, when given intralaryngeally at 10−4 M, diminished or abolished the responses to the CO2… CONTINUE READING


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