Effects of Cancer Therapy Targeting Vascular Endothelial Growth Factor Receptor on Central Blood Pressure and Cardiovascular System.

@article{Moreo2016EffectsOC,
  title={Effects of Cancer Therapy Targeting Vascular Endothelial Growth Factor Receptor on Central Blood Pressure and Cardiovascular System.},
  author={Antonella Maurizia Moreo and Paola Vallerio and Riccardo Ricotta and Miriam Stucchi and Mattia Pozzi and Francesco Musca and Paolo Meani and Alessandro Maloberti and Rita Facchetti and Sara Di Bella and Maria Olga Giganti and Andrea Sartore-Bianchi and Salvatore Siena and Giuseppe Mancia and Cristina Giannattasio},
  journal={American journal of hypertension},
  year={2016},
  volume={29 2},
  pages={158-62}
}
BACKGROUND In the last 2 decades, new drugs that oppose the effects of vascular endothelial growth factor receptor (VEGFR), and thus angiogenesis, have considerably improved treatment of solid tumors. These anti-VEGFR drugs, however, are burdened by several side effects, particularly relevant on heart and vessels. The aim of this study was to analyze the changes in cardiovascular structure and function associated with use of anti-VEGFR drugs. METHODS Twenty-nine patients (27 affected by renal… CONTINUE READING
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