Effects of Ca-free and EDTA-containing Tyrode solution on transmembrane electrical activity and contraction in guinea pig papillary muscle

Abstract

Guinea pig papillary muscle was exposed to Tyrode solution to which no Ca had been added (Ca-free) and to various concentrations of EDTA in either Tyrode or Ca-free Tyrode. The results were as follows: 1. During 15 to 20 min exposure to Ca-free Tyrode the force of contraction of papillary muscles initially declined rapidly and then at varying rates and to… (More)
DOI: 10.1007/BF00586077

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