Effects of Ca, Mg, and EDTA on creatine kinase activity in cerebrospinal fluid.

  title={Effects of Ca, Mg, and EDTA on creatine kinase activity in cerebrospinal fluid.},
  author={Petter Urdal and Johan H Str\omme},
  journal={Clinical chemistry},
  volume={25 1},
For one to obtain a precise estimate of creatine kinase (CK) activity in cerebrospinal fluid, the sample fraction is increased by about 10-fold over that used for serum. This increases the concentration of interfering substances, Ca being especially important. Therefore, the relationship between Ca, Mg, and EDTA was examined. Enzyme activity was maximal with 15 mmol of Mg per liter in the presence of 3 mmol of EDTA per liter, otherwise according to the (Scandinavian) recommended conditions for… CONTINUE READING

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