Effects of CD40 ligation on human keratinocyte accessory function

  title={Effects of CD40 ligation on human keratinocyte accessory function},
  author={J{\'e}r{\^o}me Grousson and Miguel Concha and Daniel R Schmitt and Josette P{\'e}guet-Navarro},
  journal={Archives of Dermatological Research},
CD40/CD40 ligand interactions are known to play a key role in the development of immune reactions, especially by enhancing the costimulatory function of professional antigen-presenting cells (APC). Little is known, however, about the role this receptor plays on occasional APC, i.e. cells that are induced to express MHC class II molecules following an inflammatory process. In this study, we used CD40 ligand-transfected cells to analyze the effect of CD40 ligation on the phenotype, as well as… CONTINUE READING