Effects of C-peptide on renal function at the early stage of experimental diabetes.

@article{Sjquist1998EffectsOC,
  title={Effects of C-peptide on renal function at the early stage of experimental diabetes.},
  author={Mats Sj{\"o}quist and Wen Wei Huang and B. L. Johansson},
  journal={Kidney international},
  year={1998},
  volume={54 3},
  pages={758-64}
}
BACKGROUND C-peptide has been reported to have biological effects on renal function early in the course of diabetes. This investigation was initiated to elucidate and amplify these findings with respect to protein leakage, hyperfiltration and renal functional reserve in diabetic rats. METHODS Acute effects of 140 minutes i.v. infusion of human C-peptide (0.5 nmol x min(-1) x kg(-1) body wt) on renal function and urinary protein leakage were studied in anesthetized diabetic male rats two weeks… CONTINUE READING
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