Effects of Biomechanical Stress on Gene Regulation in Vascular Cells

  title={Effects of Biomechanical Stress on Gene Regulation in Vascular Cells},
  author={Maria Carlstr{\"o}m},
The vascular vessel wall is constantly exposed to biomechanical forces, such as shear and tensile stress. Biomechanical forces are important for several physiological and pathological processes and have been shown to regulate a number of fundamental vascular functions, such as vascular tone and remodeling processes. The aim of the present thesis was to study the effects of biomechanical forces on the vessel wall. Intact human conduit vessels were exposed to normal or high intraluminal pressure… CONTINUE READING
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