Effects of Benzopyrene-7,8-Diol-9,10-Epoxide (BPDE) In Vitro and of Maternal Smoking In Vivo on Micronuclei Frequencies in Fetal Cord Blood

Abstract

Up to 20% of pregnant women smoke and there is indirect evidence that certain tobacco-specific metabolites can cross the placental barrier and are genotoxic to the fetus. The presence of micronuclei results from chromosome damage and reflects the degree of underlying genetic instability. Fetal blood was obtained from the cord blood of 143 newborns (102 from… (More)
DOI: 10.1203/01.pdr.0000228327.63820.41

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@article{Zalacan2006EffectsOB, title={Effects of Benzopyrene-7,8-Diol-9,10-Epoxide (BPDE) In Vitro and of Maternal Smoking In Vivo on Micronuclei Frequencies in Fetal Cord Blood}, author={Marta Zalaca{\'i}n and Luis Sierrases{\'u}maga and Carlos Larra{\~n}naga and Ana Pati{\~n}o-Garc{\'i}a}, journal={Pediatric Research}, year={2006}, volume={60}, pages={180-184} }