Mechanism of lipid peroxide formation in polychlorinated biphenyls (PCB) and dichlorodiphenyltrichloroethane (DDT)-poisoned rats.
Polychlorinated biphenyls (PCBs) are highly toxic persistent environmental pollutants. They were produced commercially by catalytic chlorination of biphenyls producing complex mixtures of multiple isomers. They are used as diluents, fluids for capacitors, transformers and flame retardants . Aroclor 1254 is a commercial mixture of PCBs contains about 54% of chlorine by weight, resistant to degradation and traverses the food chain .