• Corpus ID: 19023974

Effects of Aqueous Seed Extract of Persea americana Mill . ( Avocado ) on Blood Pressure and Lipid Profile in Hypertensive Rats

  title={Effects of Aqueous Seed Extract of Persea americana Mill . ( Avocado ) on Blood Pressure and Lipid Profile in Hypertensive Rats},
  author={Kate Evbu Imafidon and F. C. Amaechina},
The effects of aqueous seed extract of Persea americana Mill. (avocado), var. Fuerte, on blood pressures, plasma and tissue lipids of albino rats were investigated. Twenty-five rats were divided into 5 groups of 5 rats each. Group 1 (normal), group 2 (hypertensive), group 3 (hypertensive + 200 mg/kg b .wt of extract), group 4 (hypertensive + 500 mg/kg b. wt of extract) and group 5 (hypertensive + 700 mg/kg b. wt of extract). Except for group 1, which received 100% growers mash, all other groups… 

Hypoglycaemic and tissue-protective effects of the aqueous extract of persea americana seeds on alloxan-induced albino rats.

The present study provides a pharmacological basis for the folkloric use of the hot-water extract of P. americana seeds in the management of diabetes mellitus and reversed the histopathological damage that occurred in alloxan-induced diabetic rats.

Preliminary comparative effect of the aqueous extract of Persea americana seeds on the blood pressure of normotensive rabbits and rats

Results of the study showed that extract of Persea americana has blood pressure lowering effect in the rodent species evaluated, possibly with a narrow therapeutic margin.

Comparative Hepatotoxic Effects of Aqueous and Phenolic Extracts of Avocado (Persea americana ) Seed in Wistar Albino Rats

The result suggested hepatotoxic effect of aqueous and phenolic extracts of Avocado seed, therefore administration of P. americana seed extracts may contribute significantly to liver damage, at higher dose.

Histopathological effect of aqueous extract of Persea americana seed on alloxan- induced diabetic rats

It is concluded this study seems to provides a pharmacological basis for the traditional use of P. americana seeds extracts in the management of Diabetes mellitus and raises the possibility of its potential clinical usefulness.

Neuropharmacological profile of ethanolic dried seed extract of Persea americana in mice

Significant depressant effect of ethanolic extract of P. americana is revealed, justifying its ethnomedicinal use which can also serve as a lead in drug discovery and manifesting hypothermic, sedative, anticonvulsant and anti-nociceptive effects in mice.

Hypolipidemic Effect of Avocado (Persea americana Mill) Seed in a Hypercholesterolemic Mouse Model

The antioxidant activity of phenolic compounds and dietary fiber in ASF may be responsible for the hypocholesterolemic activity of ASF in a hyperlipidemic model of mice.

Protective Effects of Aqueous Extract of Persea Americana Leaves Against Secondary Sexual Traits and Histopathological Damages Induced by Antouka Super® in Male Japanese Quails (Coturnix sp)

Results demonstrate that AS had a toxic effect on secondary sexual traits and testis histology in male quail which could be alleviated by AEPAL administration at 200mg/kg of b.w.

Alleviation of Diabetic Dyslipidemia in Alloxan-Induced Diabetic Rats using Aqueous Seed Extract of Persea Americana

Results obtained from the diabetic study showed that plant extracts decreased blood glucose in a dose-dependent fashion and may support the acclaimed traditional use of Persea americana seed in controlling hyperglycemia in diabetes and its complications.

Antihyperglycemic and Antihyperlipidemic Effect of Persea americana in High Fat Diet and Low Dose Streptozotocin Induced T2DM Male Albino Wistar Rats

Overall, Persea americana mill fruit juice showed antihyperglycemic and antihyperlipidemic effect particularly through reduction of fasting blood glucose, LDL-C and increasing HDL-C in T2DM induced rats, thus it can be helpful in reducing the risk of diabetic complications.



BIOLOGICAL STUDIES OF INDIGENOUS MEDICINAL PLANTS-II: Effects of Aplotaxis Iappa Dcne on various parameters of liver metabolism in rabbits

SUMMARY : The effects of Aplotaxis lappa Dcne roots and its ethanol extract were studies on serum glutamate oxalacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline

Observations on the Pathophysiology of Weaner Pigs Fed Raw and Preheated Nigerian Mucuna pruriens (Velvet Bean) Seeds

It is suggested that raw Mucuna bean is poisonous to weaner pigs but relatively safe after preheats treatment, however, changes in hematological and serum biochemical parameters indicated poor nutrient utilization and muscle damage among pigs receiving higher levels of preheated seeds.

Defatted avocado pulp reduces body weight and total hepatic fat but increases plasma cholesterol in male rats fed diets with cholesterol.

The data suggest the presence of an appetite depressant in avocado and that avocado pulp interferes with hepatic fat metabolism in male rats fed normal and hypercholesterolemic diets.

Influence of Avocados on Serum Cholesterol

  • W. C. Grant
  • Medicine, Biology
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1960
In no individual did cholesterol values rise during avocado feeding, and of 8 patients whose cholesterol values were unchanged, 3 were diabetic and one was hypercholesterolemic.

Flavonoid intake and the risk of cardiovascular disease in women.

Flavonoid intake was not strongly associated with a reduced risk of CVD, and the nonsignificant inverse associations for broccoli, apples, and tea with CVD were not mediated by flavonoids and warrant further study.

Association between alpha 1 antitrypsin and bronchiectasis

An association between A1ATD phenotypes and bronchiectasis severity, independent of the presence of emphysema is shown, which can be important not only in terms of diagnosis but also concerning a therapeutic strategy.

Effect of mistletoe viscotoxin and phoratoxin on blood circulation.

Dietary salt‐loading attenuates endothelium‐dependent relaxation in response to histamine but not to acetylcholine in rat aortic rings

The results suggest that salt‐induced hypertension is associated with impairment of endothelium‐dependent relaxation to histamine but not to ACh, and that histamine‐induced relaxation was significantly attenuated in aortae from salt‐loaded rats.