Effects of ApoE genotype and mild cognitive impairment on implicit learning.

  title={Effects of ApoE genotype and mild cognitive impairment on implicit learning.},
  author={Selam Negash and Lindsay E Petersen and Yonas Endale Geda and David S. Knopman and Bradley F. Boeve and Glenn E. Smith and Robert J. Ivnik and Darlene V. Howard and James H. Howard and Ronald C. Petersen},
  journal={Neurobiology of aging},
  volume={28 6},
The goals were to investigate implicit learning in mild cognitive impairment (MCI), and to determine the relations of implicit learning systems to apolipoprotein E (ApoE) genotype in healthy controls. Elderly controls grouped by ApoE status (ApoE-e4 allele carriers versus ApoE-e4 allele non-carriers) and MCI patients participated in the study. Individuals in all three groups completed both contextual cueing and serial reaction time (SRT) tasks. In the former, people learn to use repeated… CONTINUE READING


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