Effects of Anion Channel Blockers on Hyposmotically Induced Amino Acid Release From the In Vivo Rat Cerebral Cortex

@article{Estevez2004EffectsOA,
  title={Effects of Anion Channel Blockers on Hyposmotically Induced Amino Acid Release From the In Vivo Rat Cerebral Cortex},
  author={A. Estevez and M. O'regan and D. Song and J. Phillis},
  journal={Neurochemical Research},
  year={2004},
  volume={24},
  pages={447-452}
}
A cortical cup model with continuous perfusion of artificial cerebrospinal fluid (containing 134 mM NaCl) was used to investigate the effects of anion channel blockers on the hyposmotically-induced release of amino acids from the in vivo rat cerebral cortex. The hyposmotic stimulus (25 mM NaCl) evoked a release of taurine, glutamate, aspartate, glycine, phosphoethanolamine and GABA. Topically applied anion channel blockers 4,4′-diisothiocyanatostilbene-2,2′-disulfonic acid (1 mM); 4-acetamido-4… Expand
Mechanisms of enhanced taurine release under Ca2+ depletion
Characteristics of basal taurine release in the rat striatum measured by microdialysis
Properties of basal taurine release in the rat striatum in vivo.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 29 REFERENCES
Cl channel blockers inhibit the volume-activated efflux of Cl and taurine in cultured neurons.
Volume regulation and the efflux of amino acids from cells in incubated slices of rat cerebral cortex. I. Characteristics of transport mechanisms.
  • R. Law
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 1996
Pharmacological characterization of swelling-induced d-[3H]aspartate release from primary astrocyte cultures.
Amino acid current through anion channels in cultured human glial cells
  • G. Roy
  • Chemistry, Medicine
  • The Journal of Membrane Biology
  • 2004
Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux.
Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures
...
1
2
3
...