Effects of Androgenic-Anabolic Steroids in Athletes

  title={Effects of Androgenic-Anabolic Steroids in Athletes},
  author={Fred Hartgens and H. P. Kuipers},
  journal={Sports Medicine},
Androgenic-anabolic steroids (AAS) are synthetic derivatives of the male hormone testosterone. They can exert strong effects on the human body that may be beneficial for athletic performance. A review of the literature revealed that most laboratory studies did not investigate the actual doses of AAS currently abused in the field. Therefore, those studies may not reflect the actual (adverse) effects of steroids. The available scientific literature describes that short-term administration of… 

The Use and Effect of Anabolic Androgenic Steroids in Sports

The use of AAS, are directly linked to gains muscle mass, strength, as well several side effects, always assigned to abusive and indiscriminate doses, it is noteworthy that the scientific literature, still has a certain lack of studies, mainly randomized, controlled, with supraphysiological doses in human, so many effects are still unknown.

Anabolic androgenic steroids effects on the immune system: a review

Several common AAS have been shown to adversely influence lymphocyte differentiation and proliferation, antibody production, Natural Killer Cytotoxic activity and the production of certain cytokines, thereby altering the immune reaction.

Biochemistry and physiology of anabolic androgenic steroids doping.

Animal and human investigations support the hypothesis that the administration of AASs might increase lean body mass, muscle mass, and maximal voluntary strength especially in men, so that they would represent an appealing form of doping for increasing power capacity, sustaining intensive training periods and, last but not least, as a cosmetic muscle makeover.

Anabolic–Androgenic Steroids

The anabolic–androgenic steroids (AAS) are a family of hormones that includes the natural male hormone, testosterone, together with a group of synthetic derivatives of testosterone that are widely abused by men to gain muscle mass and lose body fat.

Steroid Prohormones: Effects on Body Composition in Athletes

Androgenic-anabolic steroid hormones (AAS) are synthetic derivatives of the male hormone testosterone and for many years have been popular among athletes both for performance enhancement, due to

Do anabolic-androgenic steroids have performance-enhancing effects in female athletes?

Effect of multiple oral doses of androgenic anabolic steroids on endurance performance and serum indices of physical stress in healthy male subjects

No effect of multiple oral doses of AAS on endurance performance or bioserum recovery markers was found and none of the measured biochemical variables showed significant impact of Aas on physical stress level.

The Effects of Anabolic Androgenic Steroids on Performance and its Adverse Side Effects in Athletes

Despite performance benefits, numerous side-effects of anabolic androgenic steroids such as; increased sexual drive, occurrence of acne, increased body hair, aggressive behavior, fluid retention, elevated blood pressure (BP), sleeplessness, increased irritability, feelings of low libido, increased appetite, enhanced transpiration, increased feeling of well-being and depressive mood states have been reported.

Anabolic-Androgenic Steroids and Cardiometabolic Derangements

A patient who has used the vast majority of common anabolic steroids over the past three decades is looked at and how these compounds may affect long-term metabolic and cardiovascular health.

Adverse health effects of anabolic-androgenic steroids.




Effects of androgenic-anabolic steroids on neuromuscular power and body composition.

Anabolic steroids did not substantially change body composition or the objective power measurements used in this study, and the lack of significant results could not be attributed to dietary considerations.

Androgenic-Anabolic Steroid—Induced Body Changes in Strength Athletes

In AAS users, 8 weeks of self-administered AAS increased body weight, lean body mass, and limb circumferences, but decreased percentage fat compared with controls, though for some measurements only partially.

Effects of anabolic-androgenic steroids on muscular strength.

No evidence was found to support enhanced muscle strength with steroid use in eight studies in untrained normal volunteers, and anabolic steroids may slightly enhance muscle strength in previously trained athletes.

Ingestion of androgenic-anabolic steroids induces mild thyroidal impairment in male body builders.

It is concluded that high dose androgenic anabolic steroid administration leads to a relative impairment of thyroid function, whether this is due to a direct thyroid hormone release (or synthesis?).

Cardiovascular effects of androgenic-anabolic steroids.

The evidence presented in this review suggests that there are at least four hypothetical models of AAS-induced adverse cardiovascular effects: an atherogenic model involving the effects of Aas on lipoprotein concentrations, a thrombosis model involvingThe effects of Anabolic-anabolic steroid use on clotting factors and platelets, a vasospasm model, and a direct myocardial injury model.

Glucocorticoid antagonism by exercise and androgenic-anabolic steroids.

The role of androgenic-anabolic steroids as glucocorticoid antagonists requires further study and study of the effects of exercise on muscle gene expression of glucoc Corticoid-inducible proteins is needed to gain additional understanding of this mechanism of atrophy prevention.

Androgen abuse by athletes.

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  • Biology, Medicine
    Endocrine reviews
  • 1988
This particular form of drug abuse stems from the convergence of several separate misconceptions about the effects of androgen misuse on muscle mass and lean body weight.

Prospective echocardiographic assessment of androgenic-anabolic steroids effects on cardiac structure and function in strength athletes.

Echocardiographic evaluation may provide incomplete assessment of the actual cardiac condition in AAS users since it is not sensitive enough to detect alterations at the cellular level, but no conclusions can be drawn of the cardiotoxic effects of long term AAS abuse.

Anabolic steroid abuse

Education alone is probably not the answer to stopping anabolic steroid abuse but is an essential first step in combating this problem, physicians should avoid condemning individuals who choose to use anabolic steroids and encourage discussion of use with their health providers.