Effects of Anabolic Androgenic Steroids on the Reproductive System of Athletes and Recreational Users: A Systematic Review and Meta-Analysis

  title={Effects of Anabolic Androgenic Steroids on the Reproductive System of Athletes and Recreational Users: A Systematic Review and Meta-Analysis},
  author={Maria A. Christou and Panagiota A. Christou and Georgios Markozannes and Agathocles A Tsatsoulis and George Mastorakos and Stelios Tigas},
  journal={Sports Medicine},
BackgroundAnabolic androgenic steroids (AAS) are testosterone derivatives used by athletes and recreational users to improve athletic performance and/or enhance appearance. [] Key MethodMethodsAn electronic literature search was conducted using the databases MEDLINE, CENTRAL, and Google Scholar.
Diagnosis and Management of Anabolic Androgenic Steroid Use.
  • B. Anawalt
  • Medicine, Biology
    The Journal of clinical endocrinology and metabolism
  • 2019
Men who use AASs <1 year typically recover normal hypothalamic-pituitary-testicular axis function within 1 year after cessation, and men who have infertility due to high-dosage AAS use ≥1 year might benefit from short-term treatment with clomiphene or human chorionic gonadotropin.
The Prevalence of Anabolic Androgenic Steroid Misuse and its Associated Factors among Bodybuilders in Shiraz, Iran
AAS misuse was prevalent amongst male bodybuilders and its consumption seems to be associated with some desirable body composition changes (higher fat free mass and lower fat mass).
Fake anabolic androgenic steroids on the black market – a systematic review and meta-analysis on qualitative and quantitative analytical results found within the literature
It is demonstrated that substantial mean proportions of black-market AAS are counterfeit and of substandard quality, and a great need for future prevention and harm-reduction programs to protect users from these substances.
Anabolic-Androgenic Steroid Use in Sports, Health, and Society
This consensus statement provides a brief history of AAS use, an update on the science of how the authors now understand AAS to be working metabolically/biochemically, potential side effects, the prevalence of use among athletes, and the use of Aas in clinical scenarios.
Effect of Anabolic-Androgenic and Nutritional supplements on the Reproductive hormone, the Hematological parameters and baldness of athletes in Baghdad city
A significant increase in the mean of WBC, RBC, Hb, Ht, MCHC and PLT of group I compared with group II and III and baldness of athletes in Baghdad was demonstrated.
Side effects of anabolic steroids used by athletes at Unaizah Gyms, Saudi Arabia: a pilot study.
AAS products must be controlled by Saudi ministry of health and should not be taken randomly without the supervision of the healthcare professional.
Sports supplements and Anabolic Androgenic Steroids
The present study is aimed at examining the final sport supplement products in terms of banned substances and measuring the adulteration level in order to prove the safety of these products and promote public health.
How the love of muscle can break a heart: Impact of anabolic androgenic steroids on skeletal muscle hypertrophy, metabolic and cardiovascular health
The aim of this review is to explore the impact of AAS use on mechanisms of muscle hypertrophy and markers of MetS and further long-term research is warranted on the effects of Aas use on metabolic health in males and females.
Personal and psychosocial factors associated with anabolic-androgenic steroid use among Iranian male bodybuilders
Personal and psychosocial correlates of AAS use identified in this study may be helpful for the development of preventive interventions.
Current use and abuse of anabolic steroids


Effects of Abuse of Anabolic Androgenic Steroids on Iraqi Athletes
The results presented in the study confirm that abuse of AAS induces unfavorable body functions and undesirable side effects and efforts should be sought against use of these compounds outside the therapeutic frame.
Clinical review 31: Anabolic-androgenic steroids and athletes: what are the issues?
One of the series of agents that is of current interest are the anabolic-androgenic steroids, which are derivatives of testosterone, which is responsible for the androgenic and anabolic effects noted during male adolescence and adulthood.
Effects of Androgenic-Anabolic Steroids in Athletes
Although AAS administration may affect erythropoiesis and blood haemoglobin concentrations, no effect on endurance performance was observed and little data about the effects of AAS on metabolic responses during exercise training and recovery are available and, therefore, do not allow firm conclusions.
Effect of Anabolic-Androgenic Steroids on Semen Parameters and Serum Hormonal Levels in Iraqi Male Bodybuilders
Findings collectively indicated that, the use of AAS drugs have an ill effect on the general health of the users in addition to a profound impact on the reproductive functions.
Psychiatric and medical effects of anabolic-androgenic steroid use. A controlled study of 160 athletes.
  • H. Pope, D. Katz
  • Medicine, Psychology
    Archives of general psychiatry
  • 1994
Major mood disturbances associated with anabolic-androgenic steroids may represent an important public health problem for athletes using steroids and sometimes for the victims of their irritability and aggression.
MECHANISMS IN ENDOCRINOLOGY: Medical consequences of doping with anabolic androgenic steroids: effects on reproductive functions.
Detecting AASs misuse through the control network of the World Anti-Doping Agency (WADA) not only aims to guarantee fair conditions for athletes, but also to protect them from medical sequelae of Aass abuse.
Psychiatric and Medical Effects of Anabolic-Androgenic Steroid Use in Women
Dedicated women athletes exhibit not only AAS abuse, but use of many other ergogenic drugs, sometimes associated with significant morbidity, and frequently display several psychiatric syndromes which have not previously been well described.
Concomitant abuse of anabolic androgenic steroids and human chorionic gonadotrophin impairs spermatogenesis in power athletes.
The concomitant abuse of HCG and supraphysiological AAS dose cause transient impairment on semen quality in males, although spermatogenesis is maintained with this regimen despite prolonged abuse of massive doses of AAS.
Androgenic-anabolic steroid effects on serum thyroid, pituitary and steroid hormones in athletes
Endocrine responses in seven power athletes were investigated during a 12 week strength training period, when the athletes were taking high doses of andro genic-anabolic steroids, and during the 13 weeks fol lowing drug withdrawal, indicating prolonged impairment of testicular endocrine function.