Effects of Alendronate on Bone Density in Men with Primary and Secondary Osteoporosis

  title={Effects of Alendronate on Bone Density in Men with Primary and Secondary Osteoporosis},
  author={Yo-Sung Ho and Albert George Frauman and W Murray Thomson and E. R. BernsteinJeffrey I. Seeman},
  journal={Osteoporosis International},
Alendronate has been reported to increase bone mineral density (BMD) and reduce fracture risk in women with osteoporosis. As there are no proven safe and effective treatments available for men with osteoporosis, we compared the effects of alendronate (10 mg/day) on BMD, measured using dual-energy X-ray absorptiometry, in a 12-month prospective, controlled, open label study involving (i) men with primary (n= 23) or secondary osteoporosis (n= 18), (ii) postmenopausal women with primary (n= 18) or… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 16 extracted citations


Publications referenced by this paper.
Showing 1-10 of 26 references

Alendronatepreventscyclosporin A-induced osteopeniain the rat

  • SassDA, AR Bowman, Z Yuan, Y Ma, WS Jee, S. Epstein
  • 1997
1 Excerpt

Bisphosphonateaffectsthe boneremodelingtransient

  • Sissonde CastroJA
  • J BoneMiner Res
  • 1997

Effect of intermittentcyclical disodiumetidronatetherapyon bonemineral density in men with vertebral fractures

  • F Anderson, R Francis, J Bishop, D. Rawling
  • Age and Ageing 1997;26:359–65
  • 1997
1 Excerpt

Alendronatetreatmentof osteoporosisin men : short term bone mass response

  • JA Guy, PeterCP SheaM, HayesWC MorrisseyR
  • J Bone Miner Res
  • 1996

Alendronatetreatmentof osteoporosisin men: short term bone mass response.J Bone Miner Res 1996;11:s341

  • Sissonde CastroJA
  • 1996

Effectsof alendronate on plasmacalcium levels , urinary calcium excretion , and bone resorptionmarkers in normal rats : comparisonwith elcatonin , syntheticeel calcitonin

  • AR Bowman, Z Yuan, Y Ma, WS Jee, S Epstein
  • Endocrinology
  • 1996

Effectsof alendronate on plasmacalcium levels, urinary calcium excretion,and bone resorptionmarkers in normal rats: comparisonwith elcatonin, syntheticeel calcitonin.Endocrinology1996;137:2586–92

  • AzumaY, M Chokki, OhtaT, M Kiyoki
  • 1996
1 Excerpt

Prevalenceof vertebral fractures in Chinese men and women in Urban Taiwanesecommunities

  • BurgerH, GrashuisK Van DaelePL, GrobbeeDE HofmanA, HE Schutter
  • Calcif TissueInt
  • 1996

Similar Papers

Loading similar papers…