Effects of Administration of Galactooligosaccharides on the Human Faecal Microflora, Stool Weight and Abdominal Sensation

@article{Ito1990EffectsOA,
  title={Effects of Administration of Galactooligosaccharides on the Human Faecal Microflora, Stool Weight and Abdominal Sensation},
  author={Masaki Ito and Y. Deguchi and A. Miyamori and K. Matsumoto and H. Kikuchi and Y. Kobayashi and T. Yajima and T. Kan},
  journal={Microbial Ecology in Health and Disease},
  year={1990},
  volume={3},
  pages={285-292}
}
The effect of changing the human intestinal microflora by administration of Oligomate-50, which contains 52 per cent galactooligosaccharides and is produced from lactose by the action of β-D-galactosidase (produced by Aspergillus oryzae and Streptococcus thermophillus ), was investigated. Oligomate-50 (0, 4.8, 9.6 or 19.2 g/d) was given orally for 7 d to 12 volunteers in a single-blind cross-over study. Each dose included 0, 2.5, 5.0 or 10.0 g of galactooligosaccharides, respectively… Expand
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References

SHOWING 1-10 OF 21 REFERENCES
Effects of Fructooligosaccharides on Intestinal Flora and Human Health
TLDR
Clinical studies showed that fructooligosaccharides administration improved the intestinal flora, with subsequent relief of constipation, improved blood lipids in hyperlipidemia , and suppressed the production of intestinal putrefactive substances. Expand
Effects of Administration of TOS and Bifidobacterium breve 4006 on the Human Fecal Flora
TLDR
It is concluded that TOS, a new growth factor derived from lactose for Bifidobacterium, is a typical bifidus factor. Expand
Effects of Raffinose Intake on Human Fecal Microflora
The effects of four-week raffinose intake (15 g/day) on the fecal microflora and fecal properties were studied in healthy human volunteers. The significantly increasing numbers of BifidobacteriumExpand
Effect of Isomalto-oligosaccharides on Human Fecal Flora
TLDR
After the administration of isomaltooligosaccharides to healthy adult men and senile persons, the numbers of bifidobacteria in the feces increased and the consistency of feces was improved. Expand
Clinical effects of Bifidobacterium preparations on pediatric intractable diarrhea.
TLDR
In all patients, the stool frequency and appearance were dramatically improved within 3 to 7 days after oral administration of Bifidobacterium preparations of bifidus yogurt, and the intestinal microflora of all subjects also became normal with predominance of resident B ifidobacteria or administered B. breve. Expand
Chemical structure of three neutral trisaccharides isolated in free form from bovine colostrum.
TLDR
Three neutral trisaccharides were isolated from bovine colostrum, obtained 6 h after parturition, by l.l.c. and g.m.s. on amino silica gel and the first-named compound was a novel oligosaccharide from mammalian milk. Expand
Allolactose and 6-0-β-D-Galactopyranosyl-D-Galactose in Commercial Yogurt
Abstract Commercially available yogurts were analyzed for sugar content by gas-liquid chromatography. Allolactose (6-0- β -D-galactopyranosyl-D-glucose) and 6-0- β -D-galactopyranosyl-D-galactoseExpand
Intolerance of small amounts of lactose by individuals with low lactase levels.
TLDR
To determine the intraluminal events that occur with small amounts of lactose, 7 low lactase level subjects and 3 control subjects underwent intestinal intubation with aspiration ports in the duodenum, jejunum, and ileum. Expand
Influence of dietary fibers on fermentation in the human large intestine.
TLDR
Dietary fiber had a significant (P less than .05) effect on resultant cell wall indigestibility and VFA level and the VFA concentrations in feces of humans were significantly affected by the fiber consumed. Expand
Complex carbohydrate breakdown in the human colon.
TLDR
Results indicate that dietary fiber and mucin are degraded in the human colon. Expand
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