Effects of Acute Metabolic Stress on the Peripheral Vasopressinergic System in Schizophrenia

@article{Elman2003EffectsOA,
  title={Effects of Acute Metabolic Stress on the Peripheral Vasopressinergic System in Schizophrenia},
  author={Igor Elman and Scott E. Lukas and Susan E. Shoaf and David Rott and Caleb M Adler and Alan Breier},
  journal={Journal of Psychopharmacology},
  year={2003},
  volume={17},
  pages={317 - 323}
}
Although both vasopressin and stress have been implicated in the course of schizophrenia, it is unknown whether schizophrenic patients have altered stress-induced function of the vasopressinergic system. We examined the effects of acute metabolic stress induced by pharmacological doses (40 mg/kg) of 2-deoxyglucose (2DG) on plasma concentrations of vasopressin in 13 patients with schizophrenia (with no history of polydipsia and hyponatremia) and 12 healthy control subjects. Baseline vasopressin… CONTINUE READING

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